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Structural Biophysics
We focus on atomic resolution studies of HIV : human interactions, particularly the role of RNA - protein complexes in establishing viral infection in the cell.
RNAs and their protein complexes are one of the most difficult systems to study as single molecules. Thus, we are also involved in challenge-driven development of biophysical methods that span Cryo-EM, NMR spectroscopy, X-ray crystallography, MD simulations and Mass Spectroscopy.
Our long term goal is to lead AI/ML and molecular modelling-driven structural biology on-chip to solve the biggest health security challenges of our generation.
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